CBLB
Gene Ontology Biological Process
- T cell activation [IMP]
- immune response [IMP]
- intracellular signal transduction [IMP]
- negative regulation of T cell receptor signaling pathway [IMP]
- negative regulation of alpha-beta T cell proliferation [IMP]
- positive regulation of T cell anergy [IMP]
- positive regulation of protein catabolic process [IMP]
- signal transduction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CBL
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Association of a new c-Cbl related protein with the very first stages of apoptosis induction.
This study investigates the involvement of the c-cbl proto-oncogene during the first stages of the apoptotic process. We have already shown that a c-Cbl aptotosis-related protein of 90 kDa (CARP 90) is detected very rapidly in the cytoplasm as well as in the nucleus of murine thymocytes after hydrocortisone (HC) treatment. We report here that this protein appeared as well ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID