BAIT
TOR1
SPBC30D10.10c
phosphatidylinositol kinase Tor1
GO Process (8)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- TOR signaling [TAS]
- cell aging [TAS]
- cellular response to nitrogen starvation [IMP]
- cellular response to osmotic stress [IMP]
- phosphatidylinositol-mediated signaling [NAS]
- positive regulation of conjugation with cellular fusion [IMP]
- regulation of conjugation with cellular fusion [IMP]
- response to temperature stimulus [IMP]
Gene Ontology Molecular Function
Schizosaccharomyces pombe (972h)
PREY
RAD51
rhp51, SPAC644.14c
RecA family recombinase Rad51/Rhp51
GO Process (9)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- double-strand break repair via homologous recombination [ISS]
- homologous recombination-dependent replication fork processing [IMP]
- mating type switching [IGI]
- meiotic DNA double-strand break formation [TAS]
- meiotic DNA repair synthesis [IMP]
- meiotic gene conversion [IDA]
- mitotic recombination [IGI]
- strand invasion [IDA]
- telomere maintenance [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
TORC2 is required to maintain genome stability during the S phase in fission yeast.
DNA damage can occur due to environmental insults or intrinsic metabolic processes and is a major threat to genome stability. The DNA damage response is composed of a series of well coordinated cellular processes that include activation of the DNA damage checkpoint, transient cell cycle arrest, DNA damage repair and re-entrance into the cell cycle. Here we demonstrate that mutant ... [more]
J. Biol. Chem. May. 23, 2013; 0(0); [Pubmed: 23703609]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID