BAIT

CLN3

BTS, JNCL
ceroid-lipofuscinosis, neuronal 3
GO Process (30)
GO Function (2)
GO Component (20)

Gene Ontology Molecular Function

Homo sapiens
PREY

UQCRC2

MC3DN5, QCR2, UQCR2
ubiquinol-cytochrome c reductase core protein II
GO Process (5)
GO Function (1)
GO Component (3)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach.

Scifo E, Szwajda A, Debski J, Uusi-Rauva K, Kesti T, Dadlez M, Gingras AC, Tyynelae J, Baumann MH, Jalanko A, Lalowski M

Neuronal ceroid lipofuscinoses (NCL) are the most common inherited progressive encephalopathies of childhood. One of the most prevalent forms of NCL, Juvenile neuronal ceroid lipofuscinosis (JNCL) or CLN3 disease (OMIM: 204200) is caused by mutations in the CLN3 gene on chromosome 16p12.1. Despite progress in the NCL field, the primary function of ceroid-lipofuscinosis neuronal protein 3 (CLN3) remains elusive. In ... [more]

J. Proteome Res. Mar. 07, 2013; 0(0); [Pubmed: 23464991]

Throughput

  • High Throughput

Curated By

  • BioGRID