BAIT
IGSF8
CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL, RP11-536C5.3
immunoglobulin superfamily, member 8
GO Process (5)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
IKBKAP
DYS, ELP1, FD, IKAP, IKI3, TOT1, RP11-3J11.4
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
GO Process (9)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- chromatin organization [TAS]
- immune response [TAS]
- positive regulation of cell migration [ISS]
- protein complex assembly [TAS]
- protein phosphorylation [TAS]
- regulation of protein kinase activity [IDA, TAS]
- regulation of transcription from RNA polymerase II promoter [IDA, TAS]
- signal transduction [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes.
Extracellular vesicles are emerging as a potent mechanism of intercellular communication because they can systemically exchange genetic and protein material between cells. Tetraspanin molecules are commonly used as protein markers of extracellular vesicles, although their role in the unexplored mechanisms of cargo selection into exosomes has not been addressed. For that purpose, we have characterized the intracellular tetraspanin-enriched microdomain (TEM) ... [more]
J. Biol. Chem. Apr. 26, 2013; 288(17);11649-61 [Pubmed: 23463506]
Throughput
- High Throughput
Curated By
- BioGRID