BAIT
ICAM1
BB2, CD54, P3.58
intercellular adhesion molecule 1
GO Process (18)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
- T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell [IMP]
- adhesion of symbiont to host [IDA]
- cell adhesion [IDA]
- cytokine-mediated signaling pathway [TAS]
- establishment of endothelial barrier [IGI]
- extracellular matrix organization [TAS]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [TAS]
- interferon-gamma-mediated signaling pathway [TAS]
- leukocyte cell-cell adhesion [IMP]
- leukocyte migration [IEP]
- membrane to membrane docking [IEP]
- negative regulation of endothelial cell apoptotic process [IDA]
- negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [IDA]
- positive regulation of ERK1 and ERK2 cascade [IMP]
- positive regulation of cellular extravasation [IMP]
- receptor-mediated virion attachment to host cell [IDA]
- regulation of immune response [TAS]
- regulation of leukocyte mediated cytotoxicity [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RPL9
L9, NPC-A-16, OK/SW-cl.103
ribosomal protein L9
GO Process (13)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The Intracellular Interactome of Tetraspanin-enriched Microdomains Reveals Their Function as Sorting Machineries toward Exosomes.
Extracellular vesicles are emerging as a potent mechanism of intercellular communication because they can systemically exchange genetic and protein material between cells. Tetraspanin molecules are commonly used as protein markers of extracellular vesicles, although their role in the unexplored mechanisms of cargo selection into exosomes has not been addressed. For that purpose, we have characterized the intracellular tetraspanin-enriched microdomain (TEM) ... [more]
J. Biol. Chem. Apr. 26, 2013; 288(17);11649-61 [Pubmed: 23463506]
Throughput
- High Throughput
Curated By
- BioGRID