MVK
Gene Ontology Biological Process
- cholesterol biosynthetic process [ISO, TAS]
- isopentenyl diphosphate biosynthetic process, mevalonate pathway [IDA]
- isoprenoid biosynthetic process [IDA, ISO]
- isoprenoid metabolic process [TAS]
- negative regulation of inflammatory response [ISO]
- negative regulation of translation [IDA]
- regulation of cholesterol biosynthetic process [NAS]
- sterol metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RPS20
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Identification and characterization of proteins that selectively interact with the LHR mRNA binding protein (LRBP) in rat ovaries.
Luteinizing hormone receptor (LHR) mRNA binding protein (LRBP), identified as mevalonate kinase, has been shown to be a trans factor mediating the post-transcriptional regulation of LHR mRNA expression in ovaries. LRBP binds to the coding region of LHR mRNA and accelerates its degradation. Our previous studies in an in vitro system showed that LRBP represses the translation of LHR mRNA ... [more]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID