ANXA7
Gene Ontology Biological Process
- autophagy [ISO]
- cell proliferation [IMP]
- cellular calcium ion homeostasis [IMP]
- cellular water homeostasis [IMP]
- hemostasis [IMP]
- membrane fusion [ISO]
- negative regulation of gene expression [ISO]
- regulation of cell shape [IMP]
- response to calcium ion [ISO]
- response to organic cyclic compound [ISO]
- response to salt stress [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SRI
Gene Ontology Biological Process
- calcium ion transport [IPI]
- cytoplasmic sequestering of transcription factor [IMP]
- negative regulation of heart rate [ISO]
- negative regulation of ryanodine-sensitive calcium-release channel activity [ISO]
- negative regulation of transcription regulatory region DNA binding [IMP]
- positive regulation of insulin secretion involved in cellular response to glucose stimulus [IMP]
- positive regulation of release of sequestered calcium ion into cytosol [IMP]
- proteolysis [IBA]
- regulation of calcium ion transport [ISO]
- regulation of cardiac muscle cell contraction [ISO]
- regulation of cell communication by electrical coupling involved in cardiac conduction [ISO]
- regulation of high voltage-gated calcium channel activity [ISO]
- regulation of relaxation of muscle [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [ISO]
- Z disc [IDA, ISO]
- axon [ISO]
- axon terminus [ISO]
- cell [IMP]
- chromaffin granule membrane [ISO]
- cytoplasm [IMP, ISO]
- cytosol [ISO]
- dendritic spine neck [ISO]
- endoplasmic reticulum membrane [ISO]
- extracellular vesicular exosome [ISO]
- intracellular [IDA]
- membrane [ISO]
- mitochondrion [ISO]
- nucleoplasm [ISO]
- plasma membrane [IDA, ISO]
- smooth endoplasmic reticulum [ISO]
- vesicle [IDA]
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
The lack of annexin A7 affects functions of primary astrocytes.
Annexin A7 is a Ca(2+)- and phospholipid-binding protein, which is thought to function in membrane organization and Ca(2+)-dependent signaling processes. It localizes to different cellular compartments and exists in a 47- and 51-kDa isoform with the large isoform being expressed in brain, skeletal, and heart muscle. In human temporal brain annexin A7 was found exclusively in astroglial cells. As astrocytes ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ANXA7 SRI | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.744 | BioGRID | 2675720 |
Curated By
- BioGRID