BAIT
ENT1
SPCC162.07
epsin
GO Process (4)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
END4
sla2, SPAC688.11
Huntingtin-interacting protein homolog
GO Process (10)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- G1 to G0 transition [IMP]
- actin cytoskeleton organization [IMP]
- activation of bipolar cell growth [IMP]
- cellular protein localization [IMP]
- cellular response to nitrogen starvation [IMP]
- cortical actin cytoskeleton organization [IMP]
- endocytosis [IMP]
- establishment or maintenance of actin cytoskeleton polarity [IMP]
- fungal-type cell wall organization or biogenesis [IMP]
- plasma membrane raft distribution [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Actin Filament Severing by Cofilin Dismantles Actin Patches and Produces Mother Filaments for New Patches.
BACKGROUND: Yeast cells depend on Arp2/3 complex to assemble actin filaments at sites of endocytosis, but the source of the initial filaments required to activate Arp2/3 complex is not known. RESULTS: We tested the proposal that cofilin severs actin filaments during endocytosis in fission yeast cells using a mutant cofilin defective in severing. We used quantitative fluorescence microscopy to track ... [more]
Curr. Biol. May. 29, 2013; 0(0); [Pubmed: 23727096]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Additional Notes
- ent1-delta(ac) end4-delta (tld) inviable
Curated By
- BioGRID