BAIT
PFN1
ALS18
profilin 1
GO Process (10)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- blood coagulation [TAS]
- negative regulation of actin filament bundle assembly [IMP]
- negative regulation of actin filament polymerization [IDA]
- negative regulation of stress fiber assembly [IMP]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of ATPase activity [IDA]
- positive regulation of actin filament polymerization [IGI]
- positive regulation of epithelial cell migration [IMP]
- positive regulation of ruffle assembly [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RAD51
BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA
RAD51 recombinase
GO Process (16)
GO Function (8)
GO Component (10)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- DNA recombinase assembly [TAS]
- DNA recombination [TAS]
- DNA repair [TAS]
- DNA unwinding involved in DNA replication [IDA]
- cellular response to DNA damage stimulus [IDA]
- cellular response to camptothecin [IDA]
- cellular response to ionizing radiation [IDA]
- double-strand break repair [TAS]
- double-strand break repair via homologous recombination [IDA, IMP, TAS]
- meiotic nuclear division [ISS]
- mitotic recombination [TAS]
- positive regulation of DNA ligation [IDA]
- protein homooligomerization [IPI]
- reciprocal meiotic recombination [TAS]
- regulation of double-strand break repair via homologous recombination [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Streamline proteomic approach for characterizing protein-protein interaction network in a RAD52 protein complex.
Large-scale identification of protein-protein interactions (PPIs) in functional complexes represents an efficient route to elucidate the regulatory rules of cellular functions. Whereas many methods have been developed to identify the PPIs associated with particular target/bait protein in complexes, little information is available about the interaction relationships among all components in a complex. Here, we have established a strategy of integrating ... [more]
J. Proteome Res. May. 01, 2009; 8(5);2211-7 [Pubmed: 19338310]
Throughput
- Low Throughput
Curated By
- BioGRID