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BAIT

BAI1

GDAIF

brain-specific angiogenesis inhibitor 1

GO Process (5)

GO Function (0)

GO Component (4)

Gene Ontology Biological Process

G-protein coupled receptor signaling pathway [TAS]

axonogenesis [TAS]

negative regulation of cell proliferation [TAS]

peripheral nervous system development [TAS]

signal transduction [TAS]

Gene Ontology Cellular Component

cell-cell junction [TAS]

integral component of membrane [TAS]

integral component of plasma membrane [TAS]

plasma membrane [TAS]

CRISPR Database VEGA HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

LRRC7

DENSIN

leucine rich repeat containing 7

GO Process (0)

GO Function (1)

GO Component (0)

Gene Ontology Molecular Function

protein binding [IPI]

CRISPR Database VEGA HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

Brain-Specific Angiogenesis Inhibitor-1 Signaling, Regulation and Enrichment in the Postsynaptic Density.

Stephenson JR, Paavola KJ, Schaefer SA, Kaur B, Van Meir EG, Hall RA

Brain-specific angiogenesis inhibitor-1 (BAI1) is an adhesion G protein-coupled receptor (GPCR) that has been studied primarily for its anti-angiogenic and anti-tumorigenic properties. We found that over-expression of BAI1 results in activation of the Rho pathway via a Galpha12/13-dependent mechanism, with truncation of the BAI1 N-terminus (NT) resulting in a dramatic enhancement in receptor signaling. This constitutive activity of the truncated ... [more]

J. Biol. Chem. Jun. 19, 2013; 0(0); [Pubmed: 23782696]

Throughput

Low Throughput

Curated By

BioGRID