BAIT
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
GO Process (9)
GO Function (8)
GO Component (10)
Gene Ontology Biological Process
- bile acid biosynthetic process [ISO]
- fatty acid alpha-oxidation [ISO]
- fatty acid beta-oxidation [ISO]
- fatty acid transport [ISO]
- long-chain fatty acid import [ISO]
- long-chain fatty acid metabolic process [IMP, ISO]
- methyl-branched fatty acid metabolic process [ISO]
- very long-chain fatty acid catabolic process [ISO]
- very long-chain fatty acid metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- endoplasmic reticulum [ISO]
- endoplasmic reticulum lumen [ISO, ISS]
- endoplasmic reticulum membrane [ISO]
- extracellular vesicular exosome [ISO]
- integral component of endoplasmic reticulum membrane [ISO]
- integral component of peroxisomal membrane [IDA, ISO, ISS]
- intracellular membrane-bounded organelle [IDA]
- mitochondrion [ISO]
- peroxisomal membrane [IDA, ISO]
- peroxisome [IDA, ISO]
Rattus norvegicus
PREY
ABCD1
ABC42, ALD, ALDP, AMN
ATP-binding cassette, sub-family D (ALD), member 1
GO Process (14)
GO Function (9)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- alpha-linolenic acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation [IDA, IGI]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- linoleic acid metabolic process [TAS]
- long-chain fatty acid catabolic process [IGI]
- peroxisomal long-chain fatty acid import [IGI]
- peroxisomal membrane transport [NAS]
- peroxisome organization [IDA, NAS]
- small molecule metabolic process [TAS]
- transmembrane transport [TAS]
- unsaturated fatty acid metabolic process [TAS]
- very long-chain fatty acid catabolic process [IDA, IGI]
Gene Ontology Molecular Function- ATP binding [IDA]
- ATPase activity [IDA]
- ATPase activity, coupled to transmembrane movement of substances [NAS]
- enzyme binding [IPI]
- identical protein binding [IPI]
- peroxisomal fatty-acyl-CoA transporter activity [IGI, TAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- transporter activity [NAS]
- ATP binding [IDA]
- ATPase activity [IDA]
- ATPase activity, coupled to transmembrane movement of substances [NAS]
- enzyme binding [IPI]
- identical protein binding [IPI]
- peroxisomal fatty-acyl-CoA transporter activity [IGI, TAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- transporter activity [NAS]
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix.
The beta-oxidation of fatty acids in peroxisomes produces hydrogen peroxide (H2O2), a toxic metabolite, as a bi-product. Fatty acids beta-oxidation activity is deficient in X-linked adrenoleukodystrophy (X-ALD) because of mutation in ALD-gene resulting in loss of very long chain acyl-CoA synthetase (VLCS) activity. It is also affected in disease with catalase negative peroxisomes as a result of inactivation by H2O2. ... [more]
Arch. Biochem. Biophys. Jul. 15, 2006; 451(2);128-40 [Pubmed: 16781659]
Throughput
- Low Throughput
Ontology Terms
- tissue: liver (BTO:0000759)
Additional Notes
- K(D): 4.75 x 10^-8
- surface plasmon resonance
Curated By
- BioGRID