BAIT
IRD5
CG4201, DIK, DLAK, DmIKK, DmIKKBeta, DmIKKb, Dmel\CG4201, IK, IKK, IKK-beta, IKKB, IKKbeta, IRD-5, LRK, Lak, anon-89Bd, dIKK, dIKK-beta, dIKKbeta, ird, ird5/DmIkk[beta], Dmel_CG4201
immune response deficient 5
GO Process (11)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- Toll signaling pathway [NAS, TAS]
- antibacterial humoral response [IMP]
- antimicrobial humoral response [NAS]
- defense response to virus [IMP]
- dorsal/ventral axis specification [NAS]
- peptidyl-serine phosphorylation [IDA]
- positive regulation of antibacterial peptide biosynthetic process [IMP, NAS]
- positive regulation of defense response to virus by host [IMP]
- protein catabolic process [IDA]
- protein phosphorylation [NAS]
- regulation of innate immune response [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
CG9391
142335_at, Dmel\CG9391, IMP, Dmel_CG9391
CG9391 gene product from transcript CG9391-RC
GO Process (1)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Drosophila melanogaster
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge.
The Drosophila defense against pathogens largely relies on the activation of two signaling pathways: immune deficiency (IMD) and Toll. The IMD pathway is triggered mainly by Gram-negative bacteria, whereas the Toll pathway responds predominantly to Gram-positive bacteria and fungi. The activation of these pathways leads to the rapid induction of numerous NF-κB-induced immune response genes, including antimicrobial peptide genes. The ... [more]
Proc. Natl. Acad. Sci. U.S.A. Jun. 07, 2013; 0(0); [Pubmed: 23749869]
Throughput
- High Throughput
Curated By
- BioGRID