BAIT
TAB2
7417, CG7417, Dmel\CG7417, ORF1, TAB, dTAB2, galere, Dmel_CG7417
TAK1-associated binding protein 2
GO Process (9)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- dendrite morphogenesis [IMP]
- lateral inhibition [IMP]
- male courtship behavior, veined wing generated song production [IMP]
- peptidoglycan recognition protein signaling pathway [IMP]
- positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [IMP]
- positive regulation of defense response to virus by host [IMP]
- positive regulation of protein import into nucleus, translocation [IMP]
- regulation of transcription, DNA-templated [NAS]
- response to bacterium [IMP]
Gene Ontology Molecular Function
Drosophila melanogaster
PREY
YKI
CG4005, Dmel\CG4005, YAP, Dmel_CG4005
yorkie
GO Process (13)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- border follicle cell migration [IMP]
- cell competition in a multicellular organism [IMP]
- cell fate specification [IMP]
- cell proliferation [IMP]
- morphogenesis of an epithelial sheet [IMP]
- negative regulation of apoptotic process [IMP]
- positive regulation of glial cell proliferation [IMP]
- positive regulation of growth [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of growth [IMP]
- regulation of rhodopsin gene expression [NAS]
- stem cell proliferation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge.
The Drosophila defense against pathogens largely relies on the activation of two signaling pathways: immune deficiency (IMD) and Toll. The IMD pathway is triggered mainly by Gram-negative bacteria, whereas the Toll pathway responds predominantly to Gram-positive bacteria and fungi. The activation of these pathways leads to the rapid induction of numerous NF-κB-induced immune response genes, including antimicrobial peptide genes. The ... [more]
Proc. Natl. Acad. Sci. U.S.A. Jun. 07, 2013; 0(0); [Pubmed: 23749869]
Throughput
- High Throughput
Related interactions
Curated By
- BioGRID