BAIT
BAG3
BAG-3, BIS, CAIR-1, MFM6
BCL2-associated athanogene 3
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
AKR1C4
3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA
aldo-keto reductase family 1, member C4
GO Process (11)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- androgen metabolic process [TAS]
- bile acid and bile salt transport [TAS]
- bile acid biosynthetic process [TAS]
- bile acid metabolic process [TAS]
- cellular response to jasmonic acid stimulus [IDA]
- daunorubicin metabolic process [IMP]
- doxorubicin metabolic process [IMP]
- phototransduction, visible light [TAS]
- retinoid metabolic process [TAS]
- small molecule metabolic process [TAS]
- steroid metabolic process [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-Luminescence
An interaction is inferred when a bait protein, tagged with luciferase, is enzymatically detected in immunoprecipitates of the prey protein as light emission. The prey protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag.
Publication
BAG3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity.
Bcl2-associated athanogene 3 (BAG3), a member of the BAG family of co-chaperones, plays a critical role in regulating apoptosis, development, cell motility, autophagy, and tumor metastasis, and in mediating cell adaptive responses to stressful stimuli. BAG3 carries a BAG domain, a WW domain and a proline-rich (PXXP) repeat, all of which mediate binding to different partners. To elucidate BAG3 interaction ... [more]
Mol. Cell Proteomics Jul. 03, 2013; 0(0); [Pubmed: 23824909]
Throughput
- High Throughput
Curated By
- BioGRID