BAIT
BAG3
BAG-3, BIS, CAIR-1, MFM6
BCL2-associated athanogene 3
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
FUZ
FY, NTD
fuzzy planar cell polarity protein
GO Process (14)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
- cilium assembly [ISS]
- embryonic body morphogenesis [ISS]
- embryonic skeletal system morphogenesis [ISS]
- establishment of planar polarity [ISS]
- hair follicle development [ISS]
- negative regulation of canonical Wnt signaling pathway [ISS]
- negative regulation of cell migration [IMP]
- negative regulation of cell proliferation [ISS]
- negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation [ISS]
- negative regulation of neural crest formation [ISS]
- neural tube closure [IMP, ISS]
- nonmotile primary cilium assembly [IMP]
- positive regulation of cilium assembly [IMP]
- regulation of smoothened signaling pathway [ISS]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-Luminescence
An interaction is inferred when a bait protein, tagged with luciferase, is enzymatically detected in immunoprecipitates of the prey protein as light emission. The prey protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag.
Publication
BAG3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity.
Bcl2-associated athanogene 3 (BAG3), a member of the BAG family of co-chaperones, plays a critical role in regulating apoptosis, development, cell motility, autophagy, and tumor metastasis, and in mediating cell adaptive responses to stressful stimuli. BAG3 carries a BAG domain, a WW domain and a proline-rich (PXXP) repeat, all of which mediate binding to different partners. To elucidate BAG3 interaction ... [more]
Mol. Cell Proteomics Jul. 03, 2013; 0(0); [Pubmed: 23824909]
Throughput
- High Throughput
Curated By
- BioGRID