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BAIT

CSF2

GMCSF

colony stimulating factor 2 (granulocyte-macrophage)

GO Process (9)

GO Function (1)

GO Component (1)

Gene Ontology Biological Process

dendritic cell differentiation [IDA]

negative regulation of cytolysis [IDA]

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [IDA]

positive regulation of DNA replication [IDA]

positive regulation of gene expression [IDA]

positive regulation of interleukin-23 production [IDA]

positive regulation of macrophage derived foam cell differentiation [IDA]

positive regulation of podosome assembly [IDA]

positive regulation of tyrosine phosphorylation of Stat5 protein [IDA]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

extracellular region [TAS]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

HNRNPA2B1

HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1

heterogeneous nuclear ribonucleoprotein A2/B1

GO Process (5)

GO Function (4)

GO Component (6)

Gene Ontology Biological Process

RNA splicing [TAS]

RNA transport [IDA]

gene expression [TAS]

mRNA processing [IDA]

mRNA splicing, via spliceosome [IC, TAS]

Gene Ontology Molecular Function

RNA binding [IDA]
poly(A) RNA binding [IDA]
protein binding [IPI]
single-stranded telomeric DNA binding [IDA]

Gene Ontology Cellular Component

catalytic step 2 spliceosome [IDA]

nucleoplasm [TAS]

ribonucleoprotein complex [IDA]

spliceosomal complex [IDA]

CRISPR Database HGNC Alliance of Genome Resources VEGA OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization.

Bollig F, Winzen R, Gaestel M, Kostka S, Resch K, Holtmann H

An important determinant for the expression level of cytokines and proto-oncogenes is the rate of degradation of their mRNAs. AU-rich sequence elements (AREs) in the 3(') untranslated regions have been found to impose rapid decay of these mRNAs. ARE-containing mRNAs can be stabilized in response to external signals which activate the p38 MAP kinase cascade including the p38 MAP kinase ... [more]

Biochem. Biophys. Res. Commun. Feb. 14, 2003; 301(3);665-70 [Pubmed: 12565831]

Throughput

Low Throughput

Ontology Terms

cell line: hela cell (BTO:0000567)
disease: adenocarcinoma (DOID:299)

Curated By

BioGRID