BAIT
CSF2
GMCSF
colony stimulating factor 2 (granulocyte-macrophage)
GO Process (9)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- dendritic cell differentiation [IDA]
- negative regulation of cytolysis [IDA]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [IDA]
- positive regulation of DNA replication [IDA]
- positive regulation of gene expression [IDA]
- positive regulation of interleukin-23 production [IDA]
- positive regulation of macrophage derived foam cell differentiation [IDA]
- positive regulation of podosome assembly [IDA]
- positive regulation of tyrosine phosphorylation of Stat5 protein [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SYNCRIP
GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, RP1-3J17.2
synaptotagmin binding, cytoplasmic RNA interacting protein
GO Process (7)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization.
An important determinant for the expression level of cytokines and proto-oncogenes is the rate of degradation of their mRNAs. AU-rich sequence elements (AREs) in the 3(') untranslated regions have been found to impose rapid decay of these mRNAs. ARE-containing mRNAs can be stabilized in response to external signals which activate the p38 MAP kinase cascade including the p38 MAP kinase ... [more]
Biochem. Biophys. Res. Commun. Feb. 14, 2003; 301(3);665-70 [Pubmed: 12565831]
Throughput
- Low Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567)
- disease: adenocarcinoma (DOID:299)
Curated By
- BioGRID