SRCIN1
Gene Ontology Biological Process
- negative regulation of cell adhesion [ISO]
- negative regulation of protein secretion [IMP]
- negative regulation of protein tyrosine kinase activity [ISO, ISS]
- positive regulation of protein tyrosine kinase activity [ISO, ISS]
- regulation of cell migration [ISO, ISS]
- regulation of dendritic spine morphogenesis [ISO, ISS]
- substrate adhesion-dependent cell spreading [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SYP
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- excitatory synapse [IDA, ISO]
- integral component of synaptic vesicle membrane [IBA, TAS]
- intracellular organelle [IDA]
- membrane [ISO]
- neuron projection [IDA]
- neuron projection terminus [IDA, ISO]
- presynaptic active zone [ISO]
- presynaptic membrane [ISO]
- protein complex [IDA]
- synapse [ISO]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [ISO]
- terminal bouton [IDA]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.
p140Cap (Cas-associated protein) is an adaptor protein considered to play pivotal roles in cell adhesion, growth and Src tyrosine kinase-related signaling in non-neuronal cells. It is also reported to interact with a pre-synaptic membrane protein, synaptosome-associated protein of 25 kDa, and may participate in neuronal secretion. However, properties and precise functions of p140Cap in neuronal cells are almost unknown. Here ... [more]
Throughput
- Low Throughput
Ontology Terms
- tissue: brain (BTO:0000142)
Curated By
- BioGRID