BAIT
EPAS1
ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73
endothelial PAS domain protein 1
GO Process (6)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- cellular response to hypoxia [IDA, TAS]
- myoblast fate commitment [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- regulation of transcription from RNA polymerase II promoter in response to hypoxia [TAS]
- response to hypoxia [IDA]
- transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BATF2
SARI
basic leucine zipper transcription factor, ATF-like 2
GO Process (2)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Networks of bZIP protein-protein interactions diversified over a billion years of evolution.
Differences in biomolecular sequence and function underlie dramatic ranges of appearance and behavior among species. We studied the basic region-leucine zipper (bZIP) transcription factors and quantified bZIP dimerization networks for five metazoan and two single-cell species, measuring interactions in vitro for 2891 protein pairs. Metazoans have a higher proportion of heteromeric bZIP interactions and more network complexity than the single-cell ... [more]
Science May. 10, 2013; 340(6133);730-4 [Pubmed: 23661758]
Throughput
- High Throughput
Curated By
- BioGRID