BAIT

PF14_0735

probable protein, unknown function
GO Process (0)
GO Function (0)
GO Component (0)
Plasmodium falciparum (3D7)
PREY

PF14_0649

conserved Plasmodium protein, unknown function
GO Process (0)
GO Function (0)
GO Component (0)
Plasmodium falciparum (3D7)

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A protein interaction network of the malaria parasite Plasmodium falciparum.

LaCount DJ, Vignali M, Chettier R, Phansalkar A, Bell R, Hesselberth JR, Schoenfeld LW, Ota I, Sahasrabudhe S, Kurschner C, Fields S, Hughes RE

Plasmodium falciparum causes the most severe form of malaria and kills up to 2.7 million people annually. Despite the global importance of P. falciparum, the vast majority of its proteins have not been characterized experimentally. Here we identify P. falciparum protein-protein interactions using a high-throughput version of the yeast two-hybrid assay that circumvents the difficulties in expressing P. falciparum proteins ... [more]

Nature Nov. 03, 2005; 438(7064);103-7 [Pubmed: 16267556]

Throughput

  • Low Throughput

Curated By

  • BioGRID