BAIT
MNAT1
CAP35, MAT1, RNF66, TFB3
MNAT CDK-activating kinase assembly factor 1
GO Process (25)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- 7-methylguanosine mRNA capping [TAS]
- ATP catabolic process [IDA]
- DNA repair [TAS]
- G1/S transition of mitotic cell cycle [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- cell proliferation [TAS]
- gene expression [TAS]
- mitotic cell cycle [TAS]
- nucleotide-excision repair [TAS]
- nucleotide-excision repair, DNA damage removal [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of viral transcription [TAS]
- protein complex assembly [TAS]
- protein phosphorylation [IDA]
- regulation of cyclin-dependent protein serine/threonine kinase activity [TAS]
- regulation of transcription from RNA polymerase II promoter [IDA]
- termination of RNA polymerase I transcription [TAS]
- transcription elongation from RNA polymerase I promoter [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase I promoter [TAS]
- transcription from RNA polymerase II promoter [IDA, TAS]
- transcription initiation from RNA polymerase I promoter [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription-coupled nucleotide-excision repair [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RNF41
FLRF, NRDP1, SBBI03
ring finger protein 41, E3 ubiquitin protein ligase
GO Process (10)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- extrinsic apoptotic signaling pathway [IDA]
- negative regulation of cell migration [IMP]
- negative regulation of cell proliferation [IDA]
- positive regulation of reactive oxygen species metabolic process [IMP]
- proteasomal protein catabolic process [IDA]
- protein autoubiquitination [IDA]
- protein polyubiquitination [IDA]
- regulation of MAPK cascade [IDA]
- regulation of protein kinase B signaling [IDA]
- regulation of reactive oxygen species metabolic process [IMP]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.
Ubiquitination controls the stability or function of many human proteins, thereby regulating a wide range of physiological processes. In most cases the combinatorial pattern of protein interactions that facilitate substrate recognition or modification remain unclear. Moreover, the efficiency of ubiquitination reactions can be altered by the formation of homo- and heterotypic E3-RING complexes. To establish the prevalence and nature of ... [more]
Unknown Apr. 11, 2012; 0(0); [Pubmed: 22493164]
Throughput
- High Throughput
Curated By
- BioGRID