BAIT
RAMP3
receptor (G protein-coupled) activity modifying protein 3
GO Process (9)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway involved in heart process [ISS]
- calcium ion transport [IDA]
- cellular response to estradiol stimulus [ISS]
- negative regulation of transcription, DNA-templated [IMP]
- positive regulation of establishment of protein localization to plasma membrane [IDA]
- positive regulation of receptor recycling [IDA]
- protein localization to plasma membrane [IDA]
- protein transport [IDA]
- receptor internalization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NSF
SKD2
N-ethylmaleimide-sensitive factor
GO Process (10)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- Golgi to plasma membrane protein transport [IBA]
- Golgi vesicle docking [IBA]
- exocytosis [TAS]
- intra-Golgi vesicle-mediated transport [IBA]
- plasma membrane fusion [TAS]
- positive regulation of receptor recycling [IDA]
- regulation of exocytosis [ISS]
- synaptic transmission [TAS]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Far Western
An interaction is detected between a protein immobilized on a membrane and a purified protein probe.
Publication
Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking.
RAMPs (1-3) are single transmembrane accessory proteins crucial for plasma membrane expression, which also determine receptor phenotype of various G-protein-coupled receptors. For example, adrenomedullin receptors are comprised of RAMP2 or RAMP3 (AM1R and AM2R, respectively) and calcitonin receptor-like receptor (CRLR), while a CRLR heterodimer with RAMP1 yields a calcitonin gene-related peptide receptor. The major aim of this study was to ... [more]
J. Biol. Chem. Mar. 11, 2005; 280(10);9297-307 [Pubmed: 15613468]
Throughput
- Low Throughput
Curated By
- BioGRID