BAIT

NUTF2

2700067I02Rik, AI115459, AI413596, AW546000, Ntf2, Ntf3, PP15
nuclear transport factor 2
GO Process (2)
GO Function (1)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

NUTF2

2700067I02Rik, AI115459, AI413596, AW546000, Ntf2, Ntf3, PP15
nuclear transport factor 2
GO Process (2)
GO Function (1)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Co-crystal Structure

Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.

Publication

Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP.

Bayliss R, Ribbeck K, Akin D, Kent HM, Feldherr CM, Goerlich D, Stewart M

Nuclear transport factor 2 (NTF2) is a small, homodimeric protein that binds to both RanGDP and xFxFG repeat-containing nucleoporins, such as yeast Nsp1p and vertebrate p62. NTF2 is required for efficient nuclear protein import and has been shown to mediate the nuclear import of RanGDP. We have used the crystal structures of rat NTF2 and its complex with RanGDP to ... [more]

J. Mol. Biol. Oct. 29, 1999; 293(3);579-93 [Pubmed: 10543952]

Throughput

  • Low Throughput

Curated By

  • BioGRID