BAIT

PCTP

PC-TP, StarD2, RP23-453H19.1
phosphatidylcholine transfer protein
GO Process (2)
GO Function (2)
GO Component (0)
Mus musculus
PREY

ACOT13

0610006O17Rik, Them2, RP23-92G13.5
acyl-CoA thioesterase 13
GO Process (2)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2.

Kanno K, Wu MK, Agate DS, Fanelli BJ, Wagle N, Scapa EF, Ukomadu C, Cohen DE

The Star (steroidogenic acute regulatory protein)-related transfer (START) domain superfamily is characterized by a distinctive lipid-binding motif. START domains typically reside in multidomain proteins, suggesting their function as lipid sensors that trigger biological activities. Phosphatidylcholine transfer protein (PC-TP, also known as StarD2) is an example of a START domain minimal protein that consists only of the lipid-binding motif. PC-TP, which ... [more]

J. Biol. Chem. Oct. 19, 2007; 282(42);30728-36 [Pubmed: 17704541]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
PCTP ACOT13
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
886841

Curated By

  • BioGRID