BAIT

GEMIN2

SIP1, SIP1-delta
gem (nuclear organelle) associated protein 2
Homo sapiens
PREY

RN7SL1

7L1a, 7SL, RN7SL, RNSRP1
RNA, 7SL, cytoplasmic 1
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

Implication of the SMN complex in the biogenesis and steady state level of the Signal Recognition Particle.

Piazzon N, Schlotter F, Lefebvre S, Dodre M, Mereau A, Soret J, Besse A, Barkats M, Bordonne R, Branlant C, Massenet S

Spinal muscular atrophy is a severe motor neuron disease caused by reduced levels of the ubiquitous Survival of MotoNeurons (SMN) protein. SMN is part of a complex that is essential for spliceosomal UsnRNP biogenesis. Signal recognition particle (SRP) is a ribonucleoprotein particle crucial for co-translational targeting of secretory and membrane proteins to the endoplasmic reticulum. SRP biogenesis is a nucleo-cytoplasmic ... [more]

Nucleic Acids Res. Dec. 05, 2012; 0(0); [Pubmed: 23221635]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
GEMIN2 RN7SL1
Protein-RNA
Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Low-BioGRID
-

Curated By

  • BioGRID