BAIT

BCL10

CARMEN, CIPER, CLAP, IMD37, c-E10, mE10, RP11-234D19.2

B-cell CLL/lymphoma 10

GO Process (23)

GO Function (14)

GO Component (11)

Gene Ontology Biological Process

Fc-epsilon receptor signaling pathway [TAS]

T cell receptor signaling pathway [IDA, TAS]

adaptive immune response [TAS]

cell death [IDA]

cellular response to mechanical stimulus [IEP]

innate immune response [IEP, TAS]

interleukin-6 biosynthetic process [NAS]

lymphotoxin A biosynthetic process [NAS]

negative regulation of mature B cell apoptotic process [IDA]

neural tube closure [ISS]

positive regulation of I-kappaB kinase/NF-kappaB signaling [IEP]

positive regulation of NF-kappaB transcription factor activity [IDA]

positive regulation of extrinsic apoptotic signaling pathway [IDA]

positive regulation of interleukin-8 biosynthetic process [IMP]

positive regulation of mast cell cytokine production [NAS]

positive regulation of phosphorylation [IDA]

positive regulation of protein ubiquitination [IDA]

positive regulation of transcription, DNA-templated [IDA]

protein homooligomerization [ISS, TAS]

protein oligomerization [IPI]

response to food [IDA]

response to molecule of bacterial origin [IEP]

toll-like receptor signaling pathway [IC]

Gene Ontology Molecular Function

NF-kappaB binding [IDA]
enzyme binding [IPI]
kinase activator activity [IDA]
kinase binding [IPI]
protease binding [IPI]
protein C-terminus binding [IPI]
protein binding [IPI]
protein kinase B binding [IPI]
protein kinase binding [IDA]
protein self-association [IPI]
transcription coactivator activity [IDA]
transcription factor binding [IPI]
ubiquitin binding [IDA]
ubiquitin protein ligase binding [IPI]

Gene Ontology Cellular Component

CBM complex [NAS]

T cell receptor complex [IDA]

cytoplasm [IDA]

cytoplasmic microtubule [IDA]

cytosol [IDA, TAS]

lipopolysaccharide receptor complex [IDA]

perinuclear region of cytoplasm [IDA]

plasma membrane [TAS]

protein complex [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

PREY

IL15RA

CD215, RP11-536K7.2

interleukin 15 receptor, alpha

GO Process (3)

GO Function (3)

GO Component (0)

Gene Ontology Biological Process

cell proliferation [TAS]

cytokine-mediated signaling pathway [TAS]

signal transduction [TAS]

Gene Ontology Molecular Function

cytokine receptor activity [TAS]
protein binding [IPI]
signal transducer activity [TAS]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Toward an understanding of the protein interaction network of the human liver.

Wang J, Huo K, Ma L, Tang L, Li D, Huang X, Yuan Y, Li C, Wang W, Guan W, Chen H, Jin C, Wei J, Zhang W, Yang Y, Liu Q, Zhou Y, Zhang C, Wu Z, Xu W, Zhang Y, Liu T, Yu D, Zhang Y, Chen L, Zhu D, Zhong X, Kang L, Gan X, Yu X, Ma Q, Yan J, Zhou L, Liu Z, Zhu Y, Zhou T, He F, Yang X

Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]

Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]

Throughput

High Throughput

Curated By

BioGRID