BAIT
ADAMTS4
ADAMTS-2, ADAMTS-4, ADMP-1, UNQ769/PRO1563
ADAM metallopeptidase with thrombospondin type 1 motif, 4
GO Process (3)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ZBTB16
PLZF, ZNF145
zinc finger and BTB domain containing 16
GO Process (14)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
- apoptotic process [NAS]
- cartilage development [IDA]
- central nervous system development [ISS]
- hemopoiesis [IDA, TAS]
- mesonephros development [ISS]
- myeloid cell differentiation [TAS]
- negative regulation of myeloid cell differentiation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, NAS]
- positive regulation of cartilage development [IDA]
- positive regulation of chondrocyte differentiation [IMP]
- positive regulation of fat cell differentiation [IMP]
- positive regulation of ossification [IDA]
- positive regulation of transcription, DNA-templated [IDA]
Gene Ontology Molecular Function- DNA binding [IDA, NAS]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- identical protein binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- DNA binding [IDA, NAS]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- identical protein binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [IDA]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID