BAIT
CASK
CAGH39, CAMGUK, CMG, FGS4, LIN2, MICPCH, MRXSNA, TNRC8, RP11-540L11.1
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
GO Process (7)
GO Function (2)
GO Component (11)
Gene Ontology Biological Process
- cell adhesion [TAS]
- extracellular matrix organization [TAS]
- negative regulation of cell-matrix adhesion [IMP]
- negative regulation of cellular response to growth factor stimulus [IMP]
- negative regulation of keratinocyte proliferation [IMP]
- negative regulation of wound healing [IMP]
- nucleotide phosphorylation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
IL18
IGIF, IL-18, IL-1g, IL1F4
interleukin 18
GO Process (24)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- MAPK cascade [IMP]
- T-helper 1 type immune response [IDA]
- angiogenesis [IDA]
- cell-cell signaling [TAS]
- cellular response to organic cyclic compound [IDA]
- chemokine biosynthetic process [TAS]
- granulocyte macrophage colony-stimulating factor biosynthetic process [TAS]
- immune response [TAS]
- inflammatory response [IDA]
- interferon-gamma biosynthetic process [TAS]
- interleukin-13 biosynthetic process [TAS]
- interleukin-2 biosynthetic process [TAS]
- lipopolysaccharide-mediated signaling pathway [IDA]
- positive regulation of NK T cell proliferation [IDA]
- positive regulation of activated T cell proliferation [IDA]
- positive regulation of granulocyte macrophage colony-stimulating factor production [IDA]
- positive regulation of inflammatory response [IC]
- positive regulation of interferon-gamma production [IDA]
- positive regulation of interleukin-17 production [IDA]
- positive regulation of natural killer cell proliferation [IDA]
- positive regulation of tissue remodeling [IC]
- regulation of cell adhesion [IDA]
- sleep [ISS]
- type 2 immune response [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID