BAIT
CASK
CAGH39, CAMGUK, CMG, FGS4, LIN2, MICPCH, MRXSNA, TNRC8, RP11-540L11.1
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
GO Process (7)
GO Function (2)
GO Component (11)
Gene Ontology Biological Process
- cell adhesion [TAS]
- extracellular matrix organization [TAS]
- negative regulation of cell-matrix adhesion [IMP]
- negative regulation of cellular response to growth factor stimulus [IMP]
- negative regulation of keratinocyte proliferation [IMP]
- negative regulation of wound healing [IMP]
- nucleotide phosphorylation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PLK2
SNK, hPlk2, hSNK
polo-like kinase 2
GO Process (13)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- Rap protein signal transduction [ISS]
- Ras protein signal transduction [ISS]
- long term synaptic depression [ISS]
- long-term synaptic potentiation [ISS]
- memory [ISS]
- mitotic cell cycle checkpoint [ISS]
- mitotic spindle organization [IDA]
- negative regulation of apoptotic process [ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- protein phosphorylation [IDA]
- regulation of centriole replication [IDA, IMP]
- regulation of synaptic plasticity [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID