BAIT
CRP
PTX1, RP11-419N10.4
C-reactive protein, pentraxin-related
GO Process (10)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- acute-phase response [TAS]
- defense response to Gram-positive bacterium [TAS]
- inflammatory response [TAS]
- negative regulation of lipid storage [IDA]
- negative regulation of macrophage derived foam cell differentiation [IDA]
- negative regulation of vasodilation [IDA, IMP]
- opsonization [TAS]
- positive regulation of gene expression [IDA]
- positive regulation of superoxide anion generation [IDA]
- regulation of interleukin-8 secretion [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
GLUD1
GDH, GDH1, GLUD
glutamate dehydrogenase 1
GO Process (9)
GO Function (8)
GO Component (3)
Gene Ontology Biological Process
- cellular amino acid biosynthetic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- glutamate biosynthetic process [IDA]
- glutamate catabolic process [IDA]
- glutamine metabolic process [ISS]
- positive regulation of insulin secretion [IMP]
- small molecule metabolic process [TAS]
- substantia nigra development [IEP]
- tricarboxylic acid metabolic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID