BAIT
RAPGEF1
C3G, GRF2, RP11-40A7.1
Rap guanine nucleotide exchange factor (GEF) 1
GO Process (12)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- Rap protein signal transduction [IMP]
- activation of MAPKK activity [TAS]
- cellular response to cAMP [IDA]
- cellular response to nerve growth factor stimulus [IDA]
- establishment of endothelial barrier [IMP]
- nerve growth factor signaling pathway [IDA]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of Rap GTPase activity [IDA, IMP]
- positive regulation of neuron projection development [IMP]
- regulation of cell junction assembly [IMP]
- signal transduction [NAS]
- transmembrane receptor protein tyrosine kinase signaling pathway [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
SLC20A1
GLVR1, Glvr-1, PIT1, PiT-1
solute carrier family 20 (phosphate transporter), member 1
GO Process (6)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID