BAIT
FAS
ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, RP11-399O19.7
Fas cell surface death receptor
GO Process (12)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [TAS]
- apoptotic process [IDA, TAS]
- apoptotic signaling pathway [TAS]
- cellular response to hyperoxia [IMP]
- cellular response to mechanical stimulus [IEP]
- extrinsic apoptotic signaling pathway [IMP]
- necroptotic signaling pathway [IMP]
- positive regulation of apoptotic process [IDA, IMP]
- protein complex assembly [TAS]
- regulation of apoptotic process [NAS]
- regulation of extrinsic apoptotic signaling pathway in absence of ligand [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HNRNPC
C1, C2, HNRNP, HNRPC, SNRPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
GO Process (6)
GO Function (9)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- identical protein binding [IPI]
- mRNA 3'-UTR binding [IDA]
- nucleosomal DNA binding [IDA]
- poly(A) RNA binding [IDA]
- poly(U) RNA binding [IDA]
- protein binding [IPI]
- RNA binding [NAS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- identical protein binding [IPI]
- mRNA 3'-UTR binding [IDA]
- nucleosomal DNA binding [IDA]
- poly(A) RNA binding [IDA]
- poly(U) RNA binding [IDA]
- protein binding [IPI]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID