BAIT
CDKN2C
INK4C, p18, p18-INK4C, RP11-278J17.2
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
GO Process (8)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IDA]
- cell cycle arrest [IDA]
- mitotic cell cycle [TAS]
- negative regulation of cell growth [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of phosphorylation [IDA]
- negative regulation of protein serine/threonine kinase activity [IDA]
- regulation of cyclin-dependent protein serine/threonine kinase activity [IDA]
Gene Ontology Molecular Function
Homo sapiens
PREY
GOPC
CAL, FIG, GOPC1, PIST, dJ94G16.2
golgi-associated PDZ and coiled-coil motif containing
GO Process (5)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID