BAIT
NTRK2
GP145-TrkB, TRKB, trk-B, RP11-263K15.1
neurotrophic tyrosine kinase, receptor, type 2
GO Process (18)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- activation of adenylate cyclase activity [TAS]
- brain-derived neurotrophic factor receptor signaling pathway [IMP]
- central nervous system neuron development [ISS]
- cerebral cortex development [ISS]
- learning [ISS]
- negative regulation of neuron apoptotic process [ISS]
- neuron differentiation [ISS]
- neuron migration [ISS]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of MAPK cascade [ISS]
- positive regulation of axonogenesis [ISS]
- positive regulation of cell proliferation [ISS]
- positive regulation of gene expression [ISS]
- positive regulation of neuron projection development [ISS]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISS]
- protein autophosphorylation [ISS]
- regulation of Rac GTPase activity [ISS]
- transmembrane receptor protein tyrosine kinase signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
POLR2G
RPB19, RPB7, hRPB19, hsRPB7
polymerase (RNA) II (DNA directed) polypeptide G
GO Process (15)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- 7-methylguanosine mRNA capping [TAS]
- DNA repair [TAS]
- RNA splicing [TAS]
- gene expression [TAS]
- mRNA splicing, via spliceosome [TAS]
- nuclear-transcribed mRNA catabolic process, exonucleolytic [IBA]
- nucleotide-excision repair [TAS]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [IBA]
- positive regulation of translational initiation [IBA]
- positive regulation of viral transcription [TAS]
- transcription elongation from RNA polymerase II promoter [TAS]
- transcription from RNA polymerase II promoter [IDA, TAS]
- transcription initiation from RNA polymerase II promoter [IBA, TAS]
- transcription-coupled nucleotide-excision repair [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID