BAIT
FTH1
FHC, FTH, FTHL6, HFE5, PIG15, PLIF, OK/SW-cl.84
ferritin, heavy polypeptide 1
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TICAM2
MyD88-4, TICAM-2, TIRAP3, TIRP, TRAM
toll-like receptor adaptor molecule 2
GO Process (15)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- I-kappaB kinase/NF-kappaB signaling [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- TRAM-dependent toll-like receptor 4 signaling pathway [IDA, IMP]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- cellular response to lipopolysaccharide [IDA, IMP]
- innate immune response [TAS]
- negative regulation of chemokine (C-C motif) ligand 5 production [IMP]
- negative regulation of toll-like receptor 4 signaling pathway [IDA]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- positive regulation of chemokine (C-C motif) ligand 5 production [IMP]
- positive regulation of interleukin-18-mediated signaling pathway [IMP]
- positive regulation of toll-like receptor 4 signaling pathway [IDA, IMP]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID