BAIT
ING4
p29ING4, My036
inhibitor of growth family, member 4
GO Process (15)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [IDA]
- DNA replication [IDA]
- apoptotic process [IDA]
- cell cycle arrest [IDA]
- chromatin organization [TAS]
- histone H3 acetylation [IDA]
- histone H4-K12 acetylation [IDA]
- histone H4-K16 acetylation [IDA]
- histone H4-K5 acetylation [IDA]
- histone H4-K8 acetylation [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of growth [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of apoptotic process [IDA]
- protein acetylation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MSX1
ECTD3, HOX7, HYD1, STHAG1
msh homeobox 1
GO Process (9)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- cell morphogenesis [IDA]
- embryonic nail plate morphogenesis [IMP]
- face morphogenesis [IMP]
- negative regulation of cell growth [IDA]
- odontogenesis of dentin-containing tooth [IMP]
- positive regulation of DNA damage response, signal transduction by p53 class mediator [IC]
- positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator [IDA]
- protein localization to nucleus [IDA]
- protein stabilization [IDA]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID