BAIT
BAG6
BAG-6, BAT3, D6S52E, G3, DADB-70P7.10-021
BCL2-associated athanogene 6
GO Process (14)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- brain development [ISS]
- embryo development [ISS]
- internal peptidyl-lysine acetylation [IDA]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IMP]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISS]
- kidney development [ISS]
- lung development [ISS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- negative regulation of proteolysis [ISS]
- protein stabilization [ISS]
- spermatogenesis [ISS]
- synaptonemal complex assembly [ISS]
- tail-anchored membrane protein insertion into ER membrane [IDA]
- ubiquitin-dependent protein catabolic process [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
LBP
BPIFD2
lipopolysaccharide binding protein
GO Process (22)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- acute-phase response [IEP, ISS]
- cellular defense response [ISS]
- cellular response to lipopolysaccharide [IDA]
- cellular response to lipoteichoic acid [IDA]
- defense response to Gram-negative bacterium [IDA, ISS]
- defense response to Gram-positive bacterium [IDA]
- detection of molecule of bacterial origin [IDA]
- innate immune response [IC, ISS, TAS]
- lipopolysaccharide transport [IDA]
- lipopolysaccharide-mediated signaling pathway [IDA]
- macrophage activation involved in immune response [ISS]
- negative regulation of tumor necrosis factor production [IDA]
- opsonization [IC, ISS]
- positive regulation of interleukin-6 production [IDA]
- positive regulation of interleukin-8 production [IDA]
- positive regulation of macrophage activation [IDA]
- positive regulation of respiratory burst involved in inflammatory response [ISS]
- positive regulation of toll-like receptor 4 signaling pathway [IDA]
- positive regulation of tumor necrosis factor production [IDA, ISS]
- response to lipopolysaccharide [IDA]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID