BAIT
CYFIP1
P140SRA-1, SHYC, SRA-1, SRA1
cytoplasmic FMR1 interacting protein 1
GO Process (6)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RFX6
MTCHRS, MTFS, RFXDC1, dJ955L16.1, RP5-955L16.1
regulatory factor X, 6
GO Process (10)
GO Function (6)
GO Component (1)
Gene Ontology Biological Process
- endocrine pancreas development [IMP]
- glucose homeostasis [IMP]
- pancreatic A cell differentiation [IBA, ISS]
- pancreatic D cell differentiation [IBA, ISS]
- pancreatic epsilon cell differentiation [IBA, ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of insulin secretion [IMP]
- regulation of transcription from RNA polymerase II promoter [IBA]
- type B pancreatic cell differentiation [IBA, ISS]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IBA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IBA]
- transcription regulatory region DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IBA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IBA]
- transcription regulatory region DNA binding [IDA]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID