BAIT
BNIP3
NIP3
BCL2/adenovirus E1B 19kDa interacting protein 3
GO Process (24)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
- apoptotic process [IPI]
- cell death [ISS]
- cellular response to cobalt ion [IMP]
- cellular response to hypoxia [IMP]
- cellular response to mechanical stimulus [IEP]
- defense response to virus [IDA]
- granzyme-mediated apoptotic signaling pathway [IDA]
- intrinsic apoptotic signaling pathway in response to hypoxia [IMP]
- mitochondrial fragmentation involved in apoptotic process [IDA]
- mitochondrial outer membrane permeabilization [IDA]
- mitochondrial protein catabolic process [IMP]
- negative regulation of apoptotic process [TAS]
- negative regulation of membrane potential [IDA]
- negative regulation of mitochondrial fusion [IDA]
- neuron apoptotic process [ISS]
- positive regulation of apoptotic process [IDA]
- positive regulation of autophagy [TAS]
- positive regulation of mitochondrial fission [IDA]
- positive regulation of programmed cell death [IDA]
- positive regulation of protein complex disassembly [IDA]
- positive regulation of release of cytochrome c from mitochondria [IDA]
- reactive oxygen species metabolic process [IDA]
- regulation of mitochondrial membrane permeability [IDA]
- response to hypoxia [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
HIVEP1
CIRIP, CRYBP1, GAAP, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A, RP3-451B15.2
human immunodeficiency virus type I enhancer binding protein 1
GO Process (0)
GO Function (1)
GO Component (3)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID