BAIT
SIAH1
SIAH1A
siah E3 ubiquitin protein ligase 1
GO Process (11)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- anatomical structure morphogenesis [TAS]
- apoptotic process [TAS]
- axon guidance [TAS]
- nervous system development [TAS]
- neuron apoptotic process [ISS]
- positive regulation of apoptotic process [IDA]
- positive regulation of intrinsic apoptotic signaling pathway [IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISS]
- protein catabolic process [IDA]
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process [ISS]
- ubiquitin-dependent protein catabolic process [IDA]
Gene Ontology Molecular Function
Homo sapiens
PREY
TFDP1
DP1, DRTF1, Dp-1, RP11-230F18.1
transcription factor Dp-1
GO Process (13)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [TAS]
- Notch signaling pathway [TAS]
- apoptotic process [TAS]
- cell proliferation [TAS]
- gene expression [TAS]
- intrinsic apoptotic signaling pathway [TAS]
- mitotic cell cycle [TAS]
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [TAS]
- positive regulation of transcription from RNA polymerase II promoter [TAS]
- regulation of transcription from RNA polymerase II promoter [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- transcription, DNA-templated [TAS]
- transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleoplasm [IDA, TAS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID