BAIT
CLIC4
CLIC4L, H1, MTCLIC, huH1, p64H1
chloride intracellular channel 4
GO Process (8)
GO Function (2)
GO Component (16)
Gene Ontology Biological Process
- cell differentiation [TAS]
- cellular response to calcium ion [IMP]
- chloride transmembrane transport [TAS]
- chloride transport [NAS]
- establishment or maintenance of apical/basal cell polarity [NAS]
- keratinocyte differentiation [IMP]
- negative regulation of cell migration [IDA]
- regulation of cytoskeleton organization [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [TAS]
- apical part of cell [IDA]
- cell surface [IDA]
- cell-cell junction [IDA]
- centrosome [IDA]
- cytoplasm [IDA]
- cytosol [IDA]
- extracellular vesicular exosome [IDA]
- intracellular [IDA]
- microtubule cytoskeleton [IDA]
- microvillus [IDA]
- midbody [IDA]
- mitochondrion [IDA]
- nuclear matrix [IDA]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA]
Homo sapiens
PREY
HSP90AB1
D6S182, HSP84, HSP90B, HSPC2, HSPCB, RP1-302G2.1
heat shock protein 90kDa alpha (cytosolic), class B member 1
GO Process (9)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- axon guidance [TAS]
- innate immune response [TAS]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway [TAS]
- positive regulation of nitric oxide biosynthetic process [ISS]
- regulation of interferon-gamma-mediated signaling pathway [IMP]
- regulation of type I interferon-mediated signaling pathway [IMP]
- response to unfolded protein [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID