BAIT
CDC25A
CDC25A2
cell division cycle 25A
GO Process (9)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- DNA replication [TAS]
- G1/S transition of mitotic cell cycle [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- cell proliferation [TAS]
- cellular response to UV [IDA]
- mitotic cell cycle [TAS]
- regulation of cell cycle [TAS]
- regulation of cyclin-dependent protein serine/threonine kinase activity [TAS]
- response to radiation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytosol [TAS]
- nucleoplasm [TAS]
Homo sapiens
PREY
DMD
BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85, GS1-19O24.1
dystrophin
GO Process (22)
GO Function (8)
GO Component (14)
Gene Ontology Biological Process
- cardiac muscle cell action potential [ISS]
- cardiac muscle contraction [IMP]
- cellular protein complex assembly [ISS]
- cellular protein localization [IMP]
- extracellular matrix organization [TAS]
- motile cilium assembly [TAS]
- muscle filament sliding [TAS]
- muscle organ development [NAS]
- negative regulation of peptidyl-cysteine S-nitrosylation [ISS]
- negative regulation of peptidyl-serine phosphorylation [ISS]
- peptide biosynthetic process [IDA]
- positive regulation of neuron differentiation [IMP]
- positive regulation of neuron projection development [IMP]
- positive regulation of sodium ion transmembrane transporter activity [ISS]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [ISS]
- regulation of cellular response to growth factor stimulus [IMP]
- regulation of heart rate [IMP]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [ISS]
- regulation of ryanodine-sensitive calcium-release channel activity [ISS]
- regulation of skeletal muscle contraction [ISS]
- regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion [ISS]
- regulation of voltage-gated calcium channel activity [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [TAS]
- cell surface [IDA]
- costamere [IDA]
- cytosol [TAS]
- dystrophin-associated glycoprotein complex [IDA, NAS, TAS]
- filopodium [IDA]
- filopodium membrane [IDA]
- lateral plasma membrane [TAS]
- membrane raft [TAS]
- nucleus [IDA, TAS]
- plasma membrane [TAS]
- protein complex [IDA]
- sarcolemma [IDA]
- syntrophin complex [TAS]
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID