BAIT
CASP10
ALPS2, FLICE2, MCH4
caspase 10, apoptosis-related cysteine peptidase
GO Process (4)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NFKBIL1
IKBL, LST1, NFKBIL, DADB-70P7.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
GO Process (7)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- I-kappaB kinase/NF-kappaB signaling [IBA]
- cellular response to lipopolysaccharide [IDA]
- cytoplasmic sequestering of transcription factor [TAS]
- negative regulation of NF-kappaB transcription factor activity [IDA]
- negative regulation of lipopolysaccharide-mediated signaling pathway [IDA]
- negative regulation of toll-like receptor signaling pathway [IDA]
- negative regulation of tumor necrosis factor production [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID