BAIT
ATF4
CREB-2, CREB2, TAXREB67, TXREB
activating transcription factor 4
GO Process (20)
GO Function (7)
GO Component (6)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cellular amino acid metabolic process [TAS]
- cellular protein metabolic process [TAS]
- cellular response to glucose starvation [IMP]
- circadian regulation of gene expression [ISS]
- endoplasmic reticulum unfolded protein response [TAS]
- gluconeogenesis [ISS]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISS]
- negative regulation of oxidative stress-induced neuron death [IGI]
- positive regulation of apoptotic process [TAS]
- positive regulation of neuron apoptotic process [ISS]
- positive regulation of transcription from RNA polymerase I promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP, ISS]
- positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress [IMP, ISS]
- positive regulation of transcription, DNA-templated [IDA, IMP, ISS, NAS]
- positive regulation vascular endothelial growth factor production [IMP]
- regulation of transcription, DNA-templated [ISS]
- response to endoplasmic reticulum stress [IDA]
- transcription from RNA polymerase II promoter [ISS]
Gene Ontology Molecular Function- DNA binding [IDA, ISS]
- core promoter sequence-specific DNA binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IC]
- sequence-specific DNA binding transcription factor activity [ISS, TAS]
- transcription regulatory region DNA binding [IDA, TAS]
- DNA binding [IDA, ISS]
- core promoter sequence-specific DNA binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IC]
- sequence-specific DNA binding transcription factor activity [ISS, TAS]
- transcription regulatory region DNA binding [IDA, TAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
CKAP4
CLIMP-63, ERGIC-63, p63
cytoskeleton-associated protein 4
GO Process (0)
GO Function (1)
GO Component (3)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID