BAIT
CRY1
PHLL1
cryptochrome circadian clock 1
GO Process (15)
GO Function (11)
GO Component (1)
Gene Ontology Biological Process
- DNA damage induced protein phosphorylation [ISS]
- blue light signaling pathway [NAS]
- circadian regulation of gene expression [ISS]
- entrainment of circadian clock by photoperiod [ISS]
- gluconeogenesis [ISS]
- glucose homeostasis [ISS]
- negative regulation of G-protein coupled receptor protein signaling pathway [ISS]
- negative regulation of circadian rhythm [ISS]
- negative regulation of glucocorticoid receptor signaling pathway [ISS]
- negative regulation of protein ubiquitination [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA, ISS]
- regulation of DNA damage checkpoint [ISS]
- regulation of circadian rhythm [ISS]
- response to glucagon [ISS]
Gene Ontology Molecular Function- DNA (6-4) photolyase activity [IDA]
- DNA binding [TAS]
- blue light photoreceptor activity [NAS]
- core promoter binding [ISS]
- deoxyribodipyrimidine photo-lyase activity [IDA]
- double-stranded DNA binding [IDA]
- nuclear hormone receptor binding [IPI]
- phosphatase binding [IPI]
- protein binding [IPI]
- transcription factor binding transcription factor activity [IDA]
- ubiquitin binding [ISS]
- DNA (6-4) photolyase activity [IDA]
- DNA binding [TAS]
- blue light photoreceptor activity [NAS]
- core promoter binding [ISS]
- deoxyribodipyrimidine photo-lyase activity [IDA]
- double-stranded DNA binding [IDA]
- nuclear hormone receptor binding [IPI]
- phosphatase binding [IPI]
- protein binding [IPI]
- transcription factor binding transcription factor activity [IDA]
- ubiquitin binding [ISS]
Homo sapiens
PREY
LTBP4
ARCL1C, LTBP-4, LTBP4L, LTBP4S
latent transforming growth factor beta binding protein 4
GO Process (8)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- extracellular matrix organization [TAS]
- growth hormone secretion [TAS]
- multicellular organismal development [TAS]
- protein folding [TAS]
- regulation of cell differentiation [TAS]
- regulation of cell growth [TAS]
- regulation of proteolysis [IDA]
- regulation of transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID