DBP
Gene Ontology Biological Process
DDIT3
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- cell redox homeostasis [IDA]
- cellular protein metabolic process [TAS]
- cellular response to DNA damage stimulus [TAS]
- endoplasmic reticulum unfolded protein response [TAS]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IDA, IMP, TAS]
- mRNA transcription from RNA polymerase II promoter [IDA]
- negative regulation of canonical Wnt signaling pathway [ISS]
- negative regulation of determination of dorsal identity [IDA]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of interleukin-8 production [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress [ISS]
- positive regulation of transcription, DNA-templated [IDA]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IDA]
- regulation of DNA-templated transcription in response to stress [TAS]
- regulation of transcription involved in anterior/posterior axis specification [ISS]
- regulation of transcription, DNA-templated [IMP]
- response to endoplasmic reticulum stress [IDA]
- response to unfolded protein [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein heterodimerization activity [TAS]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription corepressor activity [TAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [ISS]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein heterodimerization activity [TAS]
- sequence-specific DNA binding transcription factor activity [NAS]
- transcription corepressor activity [TAS]
- transcription factor binding [IPI]
- transcription regulatory region DNA binding [ISS]
Gene Ontology Cellular Component
- CHOP-C/EBP complex [TAS]
- cytosol [TAS]
- nucleoplasm [IDA, TAS]
- nucleus [IDA, TAS]
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| DBP DDIT3 | FRET FRET An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins. | High | - | BioGRID | - | |
| DDIT3 DBP | FRET FRET An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins. | High | - | BioGRID | - |
Curated By
- BioGRID