BAIT
EGR2
AT591, CMT1D, CMT4E, KROX20
early growth response 2
GO Process (13)
GO Function (8)
GO Component (2)
Gene Ontology Biological Process
- brain development [TAS]
- cellular response to cAMP [IBA]
- cellular response to gonadotropin stimulus [IBA]
- fat cell differentiation [ISS]
- myelination [IBA]
- negative regulation of apoptotic process [IBA]
- peripheral nervous system development [TAS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [ISS]
- protein export from nucleus [ISS]
- regulation of neuronal synaptic plasticity [IBA]
- skeletal muscle cell differentiation [IBA]
- transcription from RNA polymerase II promoter [ISS]
Gene Ontology Molecular Function- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [ISS]
- ubiquitin protein ligase binding [IPI]
- RNA polymerase II activating transcription factor binding [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription regulatory region DNA binding [ISS]
- ubiquitin protein ligase binding [IPI]
Homo sapiens
PREY
NDUFS2
CI-49
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID