BAIT
ABCG8
GBD4, STSL
ATP-binding cassette, sub-family G (WHITE), member 8
GO Process (10)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- cholesterol efflux [IGI]
- cholesterol homeostasis [IMP]
- excretion [IGI]
- intestinal cholesterol absorption [IC]
- negative regulation of intestinal cholesterol absorption [IMP]
- negative regulation of intestinal phytosterol absorption [IMP]
- small molecule metabolic process [TAS]
- sterol transport [TAS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ANG
ALS9, HEL168, RAA1, RNASE4, RNASE5
angiogenin, ribonuclease, RNase A family, 5
GO Process (21)
GO Function (10)
GO Component (8)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis [IDA]
- actin filament polymerization [ISS]
- activation of phospholipase A2 activity [IMP]
- activation of phospholipase C activity [IMP]
- activation of protein kinase B activity [IMP]
- angiogenesis [IDA, IMP, TAS]
- cell communication [NAS]
- cell migration [IMP]
- diacylglycerol biosynthetic process [IDA]
- homeostatic process [NAS]
- negative regulation of smooth muscle cell proliferation [IDA]
- nucleic acid phosphodiester bond hydrolysis [TAS]
- oocyte maturation [NAS]
- ovarian follicle development [NAS]
- placenta development [NAS]
- positive regulation of endothelial cell proliferation [IDA]
- positive regulation of phosphorylation [IDA]
- positive regulation of protein secretion [IDA, ISS]
- rRNA transcription [IMP]
- response to hormone [IDA]
- response to hypoxia [IDA, NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID