BAIT
MYOD1
MYF3, MYOD, PUM, bHLHc1
myogenic differentiation 1
GO Process (15)
GO Function (10)
GO Component (5)
Gene Ontology Biological Process
- cellular response to estradiol stimulus [ISS]
- histone H3 acetylation [ISS]
- histone H4 acetylation [ISS]
- muscle cell differentiation [TAS]
- muscle cell fate commitment [ISS]
- muscle organ development [TAS]
- myotube cell development [IDA]
- positive regulation of muscle cell differentiation [IDA, TAS]
- positive regulation of myoblast fusion [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA, ISS]
- protein phosphorylation [TAS]
- regulation of RNA splicing [IDA]
- regulation of transcription from RNA polymerase II promoter [TAS]
- skeletal muscle tissue development [TAS]
- transcription from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function- E-box binding [ISS]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [ISS]
- core promoter binding [ISS]
- nuclear hormone receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [ISS]
- transcription coactivator activity [TAS]
- E-box binding [ISS]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [ISS]
- core promoter binding [ISS]
- nuclear hormone receptor binding [IPI]
- protein binding [IPI]
- protein heterodimerization activity [ISS]
- transcription coactivator activity [TAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
PSME2
PA28B, PA28beta, REGbeta
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
GO Process (21)
GO Function (0)
GO Component (5)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [TAS]
- G1/S transition of mitotic cell cycle [TAS]
- RNA metabolic process [TAS]
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- apoptotic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mitotic cell cycle [TAS]
- negative regulation of apoptotic process [TAS]
- negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- protein polyubiquitination [TAS]
- regulation of apoptotic process [TAS]
- regulation of cellular amino acid metabolic process [TAS]
- regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- small molecule metabolic process [TAS]
- viral process [TAS]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Mol. Syst. Biol. Oct. 13, 2011; 7(0);536 [Pubmed: 21988832]
Throughput
- High Throughput
Curated By
- BioGRID