MVP
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PLSCR1
Gene Ontology Biological Process
- acute-phase response [ISS]
- apoptotic process [IDA]
- defense response to virus [IMP]
- negative regulation of viral genome replication [IMP]
- phosphatidylserine biosynthetic process [ISS]
- phospholipid scrambling [IDA]
- platelet activation [NAS]
- positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity [IDA]
- positive regulation of gene expression [IMP]
- positive regulation of innate immune response [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of Fc receptor mediated stimulatory signaling pathway [ISS]
- regulation of mast cell activation [ISS]
- response to interferon-beta [IMP]
Gene Ontology Molecular Function- CD4 receptor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- SH3 domain binding [IDA]
- calcium ion binding [IDA, NAS]
- enzyme binding [IPI]
- epidermal growth factor receptor binding [IPI]
- phospholipid scramblase activity [IDA]
- protein binding [IPI]
- CD4 receptor binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- SH3 domain binding [IDA]
- calcium ion binding [IDA, NAS]
- enzyme binding [IPI]
- epidermal growth factor receptor binding [IPI]
- phospholipid scramblase activity [IDA]
- protein binding [IPI]
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Toward an understanding of the protein interaction network of the human liver.
Proteome-scale protein interaction maps are available for many organisms, ranging from bacteria, yeast, worms and flies to humans. These maps provide substantial new insights into systems biology, disease research and drug discovery. However, only a small fraction of the total number of human protein-protein interactions has been identified. In this study, we map the interactions of an unbiased selection of ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
MVP PLSCR1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID